Global Osteosarcoma News

From the National Cancer Institute

• NIH researchers discover tissue biomarker that may indicate higher risk of aggressive breast cancer development and death
  A series of tissue changes may be associated with an increased risk of developing aggressive breast cancer among women with benign breast disease, and poorer rates of survival among women with invasive breast cancer.
• Incidence rates of some cancer types have risen in people under age 50
  From 2010 through 2019, the incidence of 14 cancer types rose among people under age 50. However, the incidence of 19 other cancer types has decreased among this population.
• Annual Report to the Nation: Cancer deaths continue to decline
  Overall death rates from cancer declined steadily among men and women from 2001 through 2022, even during the first two years of the COVID-19 pandemic, according to the 2024 Annual Report to the Nation on the Status of Cancer.
• Combination immunotherapy shrank a variety of metastatic solid cancers
  A new form of personalized cancer immunotherapy, known as tumor infiltrating lymphocyte (TIL) therapy, dramatically improved the treatment’s effectiveness in patients with metastatic gastrointestinal cancers.
• Daily physical activity, even at light intensities, linked to lower cancer risk
  A study of 85,000 older adults in the U.K. suggests that light- and moderate-to-vigorous-intensity daily physical activity can reduce cancer risk. The number of steps taken daily may be more important for cancer risk than the intensity of activity, the study shows.
• Gene therapy shows clinical benefit in patients with a debilitating disorder caused by HPV
  An NCI clinical trial showed that an experimental gene therapy called PRGN-2012 may be an effective treatment for recurrent respiratory papillomatosis, which is caused by HPV 6 and HPV 11.
• In five cancer types, prevention and screening have been major contributors to saving lives
  Over the past 45 years, the majority of deaths averted from breast, cervical, colorectal, lung, and prostate cancer were due to prevention and screening, rather than treatment advances, NCI researchers have found.
• Researchers uncover new role of mutant RAS proteins in some of the deadliest cancers
  A new study led by NCI researchers shows that mutant RAS proteins help release a nuclear protein from a complex transported from the nucleus to the cytoplasm, kicking off a series of events that lead to the breakdown of a tumor suppressor protein.